Mod GRF (1-29)(CJC-1295 no DAC) CJC1295 without DACfirstname.lastname@example.org
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Modified GRF (1-29), CJC-1295 no DAC
Modified Growth Releasing Factor aminos 1-29, usually referred to as Modified GRF (1-29) or “ModGRF(1-29),” also known as CJC-1295 without DAC, is a synthetic analog of the endogenous peptide signaling hormone Growth Hormone Releasing Hormone (GHRH). Endogenously produced GHRH has 44 amino acids in its chain structure. A truncated synthetic form of GHRH called Sermorelin or GRF 1-29 has 29 amino acids; Modified GRF (1-29) is further changed in that it has four substituted aminos in its chain that serve the purposes of preventing degradation and oxidation in manufacture and transport as well as in vivo, while also increasing binding affinity to the GHRH receptors.
Molecular formula: C152H252N44O42
Molar Mass: 3368.7
CJC-1295 DAC vs. CJC-1295 No DAC
CJC-1295 DAC and CJC-1295 (also known as Modified GRF 1-29) are both Growth Hormone Releasing Hormones (GHRH). Their action in the human body is identical but the difference between the two peptides are the span of the half-life. Modified GRF 1-29 and Sermorelin have a very short acting half-life of about 30 minutes, while CJC-1295 DAC has a half-life that can last up to approximately 8 days. Many a scientist have reported that the short half-life of Sermorelin and Modified GRF 1-29 is considered to be much more natural as they produce a short pulse of Human Growth Hormone.
Combine Mod GRF 1-29 with a GHRP
Mod GRF 1-29 best shows its value when taken at the same time as a GHRP product, rather than used alone. For any given amount of added GH production, less of a GHRP is needed when the GHRP is stacked with Mod GRF. Or if using the same amount of a GHRP, a greater increase in GH production may be produced.
Example usages are 100 mcg of Mod GRF 1-29 taken at the same time as 100 mcg of GHRP-6 or ipamorelin. Such dosings will provide at least as much GH release as for example 300 mcg of either of these GHRP products taken alone.
The combination of Mod GRF 1-29 and a GHRP is synergistic. The GHRP stimulates a pulse of GH release, and the Mod GRF amplifies it.
When to use Mod GRF 1-29
Wherever a moderate dose GH cycle might be considered, a combination of Mod GRF 1-29 and a GHRP may be considered as an alternate. Availability, cost, or personal preference could be reasons to favor the peptide stack.
Reasons to consider using a peptide stack with Mod GRF can include increased fat loss, improved muscle gain when used in combination with anabolic steroids, cosmetic improvement of the skin, and improved healing from injury.
Mod GRF 1-29 does not need to be cycled. Generally it’s more efficient to target its use to times where accelerated improvement in body composition or muscle mass is desired. However, it can also be used on an ongoing basis where the goal is an ongoing increase of GH levels. I recommend that ongoing dosing of a Mod GRF 1-29 peptide stack should be at the lower end of the recommend range. Alternately, dosing can be full-strength, but only once a day, with injection timed shortly prior to sleep.
How to use Mod GRF 1-29
I ordinarily recommend a dosage of 100 mcg Mod GRF at a time, simultaneous with injection of a GHRP. For maximum effect, dosing is preferably three times per day at times of low blood sugar, for example about 30 minutes before a meal, but where use is ongoing, a common use is once per day prior to sleep.
Mod GRF 1-29 is typically provided in vials containing 2 mg of lyophylized powder, though the amount can vary. The contents should be reconstituted by adding a convenient amount of sterile or bacteriostatic water. If for example 2 mL is chosen and the dosing of the vial is 2 mg, the resulting solution then has a concentration of 1 mg/mL, or 1000 mcg/mL.
At time of dosing, an insulin syringe is used to draw and then inject the desired amount. In the above example, a 100 mcg dose would require a volume of 0.10 mL, or “10 IU” as marked on an insulin syringe.Injection may be subcutaneous, intramuscular, or intravenous, according to personal preference. If desired, peptide solutions from other vials, such as a vial of a GHRP product, may also be drawn into the same syringe. This reduces the total number of injections required.
Mod GRF 1-29 and sleep
Mod GRF 1-29 taken before sleep can aid in falling asleep and sometimes has the side effect of increasing vividness of dreams.
The natural hormone GHRH also has been found in the scientific literature to promote sleep, so it is not surprising that this analog does so as well.