Premixed Tablet Powder

Tablet(pills) is an solid dosage form which consist of one or more active ingredient with excipients.Excipients are very important part of the tablet formulation,they are pharmacologically inactive substances included in the formulation which is used as a carrier of active ingredient.Here are examples of the ready mix tablet binder with excipients premixed formula and percentage of each item:
1) A simple and cost effective Pre-Mixed Binder Formula.
This formula contains 2 basic but very effective excipients – Microcrystalline Cellulose USP and Magnesium Stearate NF. Microcrystalline Cellulose has a very high binding capability and creates tablets that are extremely hard, stable, yet disintegrate rapidly. Magnesium Stearate is a popular lubricant because it also acts as a glidant and anti­adherent.
Contains:
Microcrystalline Cellulose USP (98.4%) – binder.
Magnesium Stearate NF (1.6%) – lubricant.
(Note:MCC USP 102 has larger particles which are more round and dense. It is not as fluffy and light as MCC USP 101, therefore MCC USP 102 has better flow properties than MCC USP 101.)

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2) A premium, top of the line, pre-mixed excipient formula.
It is mixed with a high performance tablet lubricant which is not sensitive to over­mixing when active ingredients are added. This powder formula has excellent flow properties and will not stick to punches. Pressed tablets are shiny and very hard, yet disintegrate very rapidly.
Contains:
Microcrystalline Cellulose USP (87%) – main excipient.
Copovidone USP (5%) – sustained release agent / hardener.
Croscarmellose Sodium NF (3%) – disintegrant.
Precipitated Silica USP (2%) – glidant/ anti-adherent.
Sodium Stearyl Fumarate NF (1%) – high performance tablet lubricant.

3) A premium, top of the line, pre-mixed excipient formula.
It is mixed with a high performance tablet lubricant which is not sensitive to over­mixing when active ingredients are added. This powder formula has excellent flow properties and will not stick to punches. Pressed tablets are shiny and very hard, yet disintegrate very rapidly.
Contains:
Microcrystalline Cellulose 101 USP (87%) – main binder.
Copovidone USP (5%) – sustained release agent / hardener.
Croscarmellose Sodium NF (3%) – disintegrant.
Silicon Dioxide USP (2%) • glidant / anti-adherent.
Sodium Stearyl Fumarate NF (1%) – high performance tablet lubricant.
FD&C Blue #1 (2%)

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4) A premium, top of the line, pre-mixed excipient formula.
It is mixed with a high performance tablet lubricant which is not sensitive to over­mixing when active ingredients are added. This powder formula has excellent flow properties and will not stick to punches. Pressed tablets are shiny and very hard, yet disintegrate very rapidly.
Contains:
Microcrystalline Cellulose 101 USP (84%) – main binder.
Copovidone USP (5%) – sustained release agent / hardener.
Croscarmellose Sodium NF (3%) – disintegrant.
Silicon Dioxide USP (2%) – glidant/ anti-adherent.
Sodium Stearyl Fumarate NF (1%) – high performance tablet lubricant.
FD&C Blue #2 (5%)

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5) A premium, top of the line, pre-mixed excipient formula.
It is mixed with a high performance tablet lubricant which is not sensitive to over­mixing when active ingredients are added. This powder formula has excellent flow properties and will not stick to punches. Pressed tablets are shiny and very hard, yet disintegrate very rapidly.
Contains:
Microcrystalline Cellulose USP (84%) – main binder.
Copovidone USP (5%) – sustained release agent / hardener.
Croscarmellose Sodium NF (5%) – disintegrant.
Silicon Dioxide USP (2%) • glidant/ anti-adherent.
Sodium Stearyl Fumarate NF (1%) – high performance tablet lubricant.
FD&C Red #40 (3%)

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6) A premium, top of the line; pre-mixed excipient formula.
It is mixed with a high performance tablet lubricant which is not sensitive to over­mixing when active ingredients are added. This powder formula has excellent flow properties and will not stick to punches. Pressed tablets are shiny and very hard, yet disintegrate very rapidly.
Contains:
Microcrystalline Cellulose USP (84%) – main binder.
Copovidone USP (5%) – sustained release agent / hardener.
Croscarmellose Sodium NF (3%) – disintegrant.
Silicon Dioxide USP (2%) – glidant/ anti-adherent.
Sodium Stearyl Fumarate NF (1%) – high performance tablet lubricant.
FD&C Yellow #5 (5%)

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7) A premium, top of the line pre-mixed excipient formula containing Microcrystalline Cellulose.
It is mixed with a high performance tablet lubricant which is not sensitive to over­mixing when active ingredients are added. This powder formula has excellent flow properties and will not stick to punches. Pressed tablets are shiny and very hard, yet disintegrate very rapidly.
Contains:
Microcrystalline Cellulose 102 USP (89%) – main excipient.
Copovidone USP (5%) – sustained release agent / hardener.
Croscarmellose Sodium NF (3%) – disintegrant.
Precipitated Silica USP (2%) – glidant/ anti-adherent.
Sodium Stearyl Fumarate NF (1%) – high performance tablet lubricant.

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What is needed for steroid injectables

vials group

1. machines you are needed during making injectables:
injection syringe
sterilizing filter (Sterile (Syringe) Filters (0.22um) – These are used to Sterilize the solution and make it suitable for injection without any risk to the user. This is the most important step and must be carried out properly to ensure the produce is safe to use. It is possible to use Syringe filters for smaller scale production or alternatively Vacuum pump filters which is fully automatic and makes it possible to filter many litres of Steroids with ease. The best Syringe filter will be the widest diameter possible and made of Nylon because it improves filter efficiency and approximately 100ml of Hormones will be produced by each filter before the filtration rate slows dramatically.)
sterizling filtering machine
heater
electronic scale(These are required to weigh to an accuracy of 0.01g to ensure you are able to weigh the Steroid powders acurately for the Recipe you are using)
Glass Beaker/Glass Stirring rod (100ml Beaker is adequate for small time production but neither of these are essential as anything can be used to make the initial mixture)
10ml vials or ampoules
Needles / Syringes –
capping machine
label designing and printing
sealing machine( or cimper)
label machine

2. additives you are needed during making injectables
Carrier oil – This is the Oil that all of the ingredients are suspended in, all Steroids have a Carrier Oil and the most used carrier oil in all Steroid production is Grape-seed oil. It is possible to purchase this pre-filtered, which is considerably more expensive, or to purchase it from your local Store/Super Market and there is no preference for one or the other as the entire mixture will be filtered and made Sterile during the production process.

Benzyl-benzoate (BB) – This is the solvent that holds the dissolved Steroid Compound, it allows the powder to dissolve and ensures it stays fully dissolved. Too much BB will not cause any Post Injection Pain, the most common ratio is 18%-20% of the total solutoin for BB.

Benzyl-Alcohol (BA) – This provides the shelf-life of the product and is very inexpensive and only a small amount is required with the most common ratio being 2% of the total volume of Solution. It is not reccomended to go higher than this (2%) as high BA content will cause Post Injection Soreness in some people.

3.and I also list something for you to make capsules if you want try later:

Shopping list for making capsules:
1. capsules.many sizes for choice, and most used is size ‘0’ capsules, they hold around 500mg of powder.
2. capsule making machine. most used is a cap quick with the tamper.
3. Steroid raw or ‘active’ ingredient.
4. Filler, I like to use good ole ‘all purpose flour’ but anything of the same grain will work well
5. mortar and pestle or Tupperware container or Ziploc bag.

When making capsules it is important to get the densities of the powders youll be using so that you can correctly mix them.
You’ll want to fill and weigh a reasonable selection of capsules so as to get a good number for how much of each ingredient will properly fit into a single capsule. You know how much active ingredient you want to use so that and the amount of each you can fit into capsules are the constants in the ratio and the value you want to find is the amount of filler.

If it is possible, you are welcomed to our company.if you have questions for us,
Don’t hesitate to contact via
1. send mails to duosue@chembj.com
2.instant messgage:
skype:live:gina0818_2; live:emma_5789
whatsapp:+8615527058237; +8618872220799

Proper steroid injection technique

Semimade steroid oil and steroid powder contact whatsapp:+8615527058237

 

how to inject steroids the sites
If the gluteal region cannot be injected for some reason, the second choice would be the lateral portion of the thigh. Usually, intramuscular injections in the thigh are only indicated for infants and children. The vastus lateralis muscle is the only area of the thigh that should be injected intramuscularly. This site is determined by using the knee and the greater trochanter of the femur as landmarks. The greater trochanter is the bony area that you can feel where the femur joins the pelvic girdle. The mid portion of the muscle is located by measuring the handbreadth above the knee and the handbreadth below the greater trochanter. Injecting into the front of the thigh or inside of the thigh is extremely unwise. These areas contain nerves as well as a number of blood vessels.

Steroid Injections – Phase 1:
First, you´ll need to draw the steroid out of the vial, with a syringe. The most common size for injecting anabolic steroids is a 23-25ga. X 1-1.5″ needle. This size will work for all water based and oil based injectable steroids. The first thing you need to do is make sure you are using a clean, unused needle. Next, make sure the top of the vial is clean, and swab it with an alcohol pad.

(In-order to draw the liquid out of the vial, you´ll first want to pull some air into the syringe, usually the same amount as you will be drawing in for your injection if not a little more. Next, you want to hold the vial upside down and inject the air into the vial. This will increase pressure inside the vial and allow the liquid to be drawn into the syringe more easily. Once you´ve done this, and while you´re still holding the vial upside down, you need to make sure the tip of the needle is below the level of the liquid, begin to slowly pull back on the plunger and drawl the desired amount of liquid into the syringe.From here, you have the option of replacing the needle that breached the rubber stopper of the vial with a fresh needle. This is because even one pass through the rubber of a vial will blunt the tip of a needle; even if this is not visible to the naked eye, it´s still got the potential to cause additional discomfort when you inject. In many cases, it’s not uncommon for the individual to use a large drawl needle for all his steroid injections; drawl needles are often 20ga-22ga in size and will make the entire process a lot smoother.)

Steroid Injections – Phase 2:
Test 600xOnce your solution is inside the syringe, choose the area you wish to inject and clean it with a new and never before used alcohol swab. As the area is now disinfected, directly into the center of the desired injected area simply force the needle in, it won’t take much and prepare to inject. With the needle all the way in, before you inject the solution, draw back the plunger of the syringe few tenths; if any blood comes into the syringe you will need to remove it immediately and find a new spot to inject. You very well may only need to move over an inch or so or you can find a new spot and start the procedure again. Once you have found a suitable area, and this will get much easier with time, simply inject the solution, but you’re not quite done yet.

Steroid Injections – Phase 3:
With all of your steroid injections, once the solution is completely administered leave the needle in for a good 15 or so seconds and allow the steroid to settle. At this point, remove the needle and immediately place a clean, never before used cotton ball on the injected site and apply pressure and hold for approximately 20-30 seconds. At this point, you’ll remove the cotton ball and you very well may find blood on it; don’t freak out; remember, you’ve just pierced your skin. Throw the cotton ball away, and then with a little pressure massage the injected area; this will help with any potential soreness; it’s not an absolutely necessity but it can help.

Making capsules

making capsules

Things you will need to make your capules.

1. A capping device and empty gel caps. The two most por capping devices are the “Cap-M-Quick” and “The Capsule Machine”. The cap-m-quick does 50 caps at a time but you have to manually join the caps by hand. The capsule machine only does 24 caps at a time but automatically joins them for you. Both of these devices can be purchased to use either size “0” or “00” caps (size “0” caps are smaller than size “00”). I prefer the capsule machine and size “0” caps, but either device in either size is fine.

2. A scale to weigh the powders you’ll be using to make your caps. I recommend either the Palmscale 5.0 which is accurate to 0.1g and has a capacity of 200g (cost approx $60), the iBalance 201 which is accurate to 0.01g and has a capacity of 200g (cost approx $100, my favorite), or the GemPro-50 which is accurate to 0.002g and has a capacity of 10g (cost approx $150).

3. The powdered version of the compound that you plan on capping. Oral compounds such as Anavar, dnp – dinitrophenol – , Clomid, Dianabol – methandrostenolone – , nolva and Winstrol – stanozolol make good capping choices. However compounds such as Clen, T3, Femara and Arimidex should never be capped because of their small dose amounts and the inherent inaccuracies of the capping process.

4. A powdered filler that will be used to take up the space in the caps that the active compound doesn’t. Almost anything can be used as a filler, Protein Powder, Baking Soda (Sodium Bicarbonate), Corn Starch, Flour, Creatine, Lactose, Glutamine, etc.

5. A mortar and pestle to thoroughly mix the active compound and filler together. Many compounding pharmacies use a mortar and pestle to mix their ingredients together for capping and if it’s good enough for them it’s good enough for me.
Now that we have everything necessary to make our caps here’s how we do it. For the example below I’ll use the capsule machine to make 48 caps with 100mg of Aspirin (active compound) and Baking Soda (filler).

1. Load 24 empty caps into the capsule machine, then fill all 24 caps with Baking Soda (tamping powder if final caps will be tamped).

2. Empty all the Baking Soda out of the capsule machine and weigh it. Total weight = 17,160mg

3. Divide that weight (17,160mg) by the number of capsules (24) to get the total weight per cap. 17,160mg / 24 = 715mg a cap.

4. Repeat these steps with the Aspirin powder. Total weight = 11,760mg / 24 = 490mg a cap.

5. Now we need to figure out the ratio of Aspirin to Baking Soda.

100mg Aspirin = Unknown mg of Baking Soda

490mg Aspirin = 715mg Baking Soda
(100mg Aspirin x 715mg Baking Soda) / 490mg Aspirin = 146mg of Baking Soda (this is the Unknown mg of Baking Soda, and how much must be removed to make space for 100mg of Aspirin)
715mg Baking Soda – 146mg = 569mg Baking Soda (this is how much Baking Soda to use per cap)
569mg Baking Soda x 48 caps = 27,312mg Baking Soda

100mg Aspirin x 48 caps = 4800mg Aspirin

So to make 48 100mg Aspirin caps we need 4800mg of Aspirin powder and 27,312mg of Baking Soda.
This is where the simpler methods fail and give inaccurate results. As the chart below shows, different compounds (like Aspirin and Baking Soda (Sodium Bicarbonate)) weigh different amounts for the same volume. If we had simply subtracted 100mg from the Baking Soda we would not have had properly dosed caps, because to fit in 100mg of Aspirin we needed to subtract 146mg of Baking Soda.

Now that we know how much active compound and filler to use (Aspirin and Baking Soda) we need to mix them together. To do this we’ll use a mortar and pestle with the geometric dilution method, which was introduced to me by pharmguy24 on AU. What’s the geometric dilution method you ask? It’s a method used when a small amount of powder needs to be *thoroughly* mixed with a larger amount of powder. To do this you mix all of the smaller powder with an approximately equal amount of the larger powder, this blend is called “mix 1”. Then combine all of your “mix 1” with an equal amount of the larger powder and blend again, this is “mix 2”. Keep going like this until all the powders have been mixed together.

So we place all of the Aspirin powder (the smaller amount of the two different powders) in the mortar and add an equal amount of the Baking Soda (approximately 4800mg), then blend them together with the pestle for a couple of minutes. This combination is our mix 1, and it is now 9600mg (4800mg Aspirin + 4800mg Baking Soda). After it’s been blended for a few minutes add an equal amount of Baking Soda (9800mg) to your mix 1 and blend for a couple more minutes. This combination is our mix 2 and is 19,200mg (9800mg from mix 1 + 9800mg Baking Soda). After it’s been blended for a few minutes add the remaining Baking Soda (12912mg) to your mix 2 and blend for a couple more minutes.

Why go to this extra trouble? Because even though we know the amounts of Aspirin and Baking Soda we’re using are dead on, our caps will not be dosed properly if the powders are not mixed together very thoroughly.
Now we’re ready to make our caps.

1. Load both the base and top of the capsule machine with the empty gel caps (the bottom should already be loaded from weighing the powder for mixing).

2. Place the base on its stand and pour the mixed powder over the empty caps, then spread it around using the supplied plastic card so all the caps are filled.

2a. Optional: At this point you can tamp the powder down and add more powder to the caps increasing the amount they can hold. But because what we want to cap fits fine without doing that we didn’t calculate for it and wont be doing it.

3. Attach the top of the capsule machine (which contains the other halves of the caps) to the base.

4. Remove the capsule machine from its stand and press it down on your work surface applying even pressure to join the caps.

5. Remove the top from the capsule machine and press against the spring loaded plate on its back to eject the finished caps.

6. Repeat these steps until all your caps are made.

Equipment and Machines For Steroid Business//duosue@chembj.com

Equipment and Machines

Machines Required To Steroids

injection syringe

injection syringe
sterilizing filter

sterilizing filters
sterizling filtering machine
tablet press machine

tablet press machine
heater
electronic scale
beaker
Vials/ampoules group

vials group
capping machine
label designing and printing
sealing machine
label machine

 
Equipment Required To Produce Steroids

This section will walk you through the equipment one needs to produce Steroids and you will be pleased to know everything is easily sourced and inexpensive.

Carrier oil – This is the Oil that all of the ingredients are suspended in, all Steroids have a Carrier Oil and the most used carrier oil in all Steroid production is Grape-seed oil. It is possible to purchase this pre-filtered, which is considerably more expensive, or to purchase it from your local Store/Super Market and there is no preference for one or the other as the entire mixture will be filtered and made Sterile during the production process.

Sterile (Syringe) Filters (0.22um) – These are used to Sterilize the solution and make it suitable for injection without any risk to the user. This is the most important step and must be carried out properly to ensure the produce is safe to use. It is possible to use Syringe filters for smaller scale production or alternatively Vacuum pump filters which is fully automatic and makes it possible to filter many litres of Steroids with ease. The best Syringe filter will be the widest diameter possible and made of Nylon because it improves filter efficiency and approximately 100ml of Hormones will be produced by each filter before the filtration rate slows dramatically.

Benzyl-Alcohol (BA) – This provides the shelf-life of the product and is very inexpensive and only a small amount is required with the most common ratio being 2% of the total volume of Solution. It is not reccomended to go higher than this (2%) as high BA content will cause Post Injection Soreness in some people.

Benzyl-benzoate (BB) – This is the solvent that holds the dissolved Steroid Compound, it allows the powder to dissolve and ensures it stays fully dissolved. Too much BB will not cause any Post Injection Pain, the most common ratio is 18%-20% of the total solutoin for BB.

Sterile vials – Vials are easily source Online and different sizes are available – 20ml, 30ml and 50ml.

Needles / Syringes – These are part of the production process – a needle is attached to the syringe filter, which is in turn connected to the syringe.

Electric scales – These are required to weigh to an accuracy of 0.01g to ensure you are able to weigh the Steroid powders acurately for the Recipe you are using.

Glass Beaker/Glass Stirring rod (Both optional) – From Ebay or from a Laboratory supply website. A 100ml Beaker is adequate for small time production but neither of these are essential as anything can be used to make the initial mixture (a glass for exmaple) because once it passes through the syringe filter the solution is completely sterilized. This will be discussed in depth in the next section.

The above list represents all the materials required to produce steroids, they can all be sourced without much expense and it is in-fact possible to purchase everything from one website – one that specializes in Laboratory supplies.